Low-coordinate organophosphorus compounds: some stereochemical considerations
نویسندگان
چکیده
منابع مشابه
Esterases Reacting with Organophosphorus Compounds
The sixty-seven papers in this book are grouped under the following chapters: Esterase Structures, Catalytic Properties of Cholinesterases, Catalytic Properties of Paraoxonases and Related Esterases, Biology of Cholinesterases, Biology of Paraoxonases and Related Esterases, Toxicity and Degradation of Organophosphorus Compounds, Neuropathy Target Esterase, and Miscellaneous. The chapters are pr...
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Oxidative stress has recently been implicated as a factor in the mortality and morbidity induced by organophosphorus (OP) compound poisoning. An overwhelming number of research papers are based on studying at the cellular and organ level. Such studies have concluded that antioxidants can be used as an adjunct compound in the treatment of both chronic as well as acute OP poisoning. Still, the ro...
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As a consequence of organophosphorus (OP) toxins posing a threat to human life globally, organophosphorus hydrolase (OPH) has become the enzyme of choice to detoxify such compounds. Organophosphorus hydrolase was covalently immobilized onto a quartz substrate for utilization in paraoxon detection. The substrate was cleaned and modified prior to chemical attachment. Each modification step was mo...
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Many organophosphorus compounds produce a chronic toxicity that has been classified as a dying-back process in which the long axons are particularly affected. Recent evidence indicates that an essential first step in the production of the lesion is the phosphorylation of a protein that is able to hydrolyse substrates such as phenyl phenylacetate. The esterase activity of the protein is inhibite...
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Over the years, evidence has been accumulating [1, 2] that selenium is an essential nutrient in animals, preventing various serious deficiency diseases. On the other hand, no such firm proof for the need of selenium in human nutrition has been established, although several instances of beneficial effects as a result of selenium supplementation of human diet have been reported [3-5]. Although va...
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ژورنال
عنوان ژورنال: Pure and Applied Chemistry
سال: 2018
ISSN: 1365-3075,0033-4545
DOI: 10.1515/pac-2018-0912